What are some very specific events and historical developments that contributed to this now problematic unstable...

What are some very specific events and historical developments that contributed to this now problematic unstable, nationalist, and anti-west state of the Middle East?

The Iranian Revolution basically started it.

The spread of Islam

The establishment of Western model armies with officers trained in Europe at a time when nationalism was spreading like wildfire.

The consolidation of several Ottoman provinces into large states with one region declared supreme over all others.

Rapid urbanization and population growth due to the green revolution creating economic problems.

Proxy wars fought between the US and Russia, and also Saudi Arabia and Iran.

dissolution of the ottoman empire was a mistake
rather than these guys the middle-east was given to the control of wahhabi bedoins and tribal leaders

Biggest one would be the nonsensical borders established post-WWI including, predominately, Saudi Arabia. British and American influence peddling in Iran was the second biggest mistake, Support of Israel the third.

The Eternal Anglo, of course

It's a shit show, but it all started with the fall of the Ottoman Empire

It goes back much further than WW2 or the Ottomans.

Arabs would not rule themselves from the 10th century--when the empires founded by Muhammad's generals fell--until right up to the 20th century. Nearly one thousand years in which regular Arabs were excluded from power in the Middle East, instead ruled by a series of outsiders; Kurds, Persians, Turks (predominantly), and the British/French.

The Turks may have been Muslim but they still considered themselves wholly different from the Arabs they ruled over, and most Ottoman citadels were built more for segregation than defense. When the Saudis demolished the Ottoman citadel overlooking Mecca recently, that was used partially as justification; it had been built to keep Wahhabi Arabs out of Mecca.

"Anti-West" sentiment is just the latest iteration of their contempt for anything even tangentially reminiscent of foreign domination and Arab subjugation. They're also very keen to apply it to each other, for example during the Reconquista;

>Ibn Khaldûn, for instance, labeled them “weak-minded,” a people who had lost their group feeling, instinct for cooperation, and ability to take power as a result of the annihilation of their Arab Dynasty. According to his words, the Spanish Muslims had been enslaved by tyranny and become used to being humiliated. Ibn Khaldûn pushed his analysis further: “The [Muslim] Spaniards are found to assimilate themselves to the [Christian] Galician nations in their dress, their emblems and most of their customs and conditions. This goes so far that they even draw pictures on the walls and have them in buildings and houses. The intelligent observer will draw from this the conclusion that it is a sign of being dominated by others.”

Israel wants to destabilize the region for its own benefit