What's a good way to package and present campaign setting information?

Give out the information organically ingame.

Can I read it?

They won't read it. If you say it's mandatory, they won't read it and will lie about it to your face.

Read it to them, do a powerpoint presentation in simple language if you need to, hand it to them printed out at session zero, and start session one with an exam on the material you provided. No pass mark? No play.

That sounds quite harsh.

Build a wiki, you might actually get one person in the group to read it.

Otherwise, I have to give Paizo some credit, as far as making adventures goes. Gazetteers and Player's Guides can be really helpful and if they are properly sized -- 20 pages or so total -- your players might actually read it, especially if you take the $10 hit or so to get it printed at Staples or something as a nice ringed booklet. Of those 20 pages, you don't want to just vomit up fluff, either, so blend in some crunch that your players can take advantage of, some pretty pictures, and a map. The Curse of the Crimson Throne one is a pretty good example. It's 17 pages of useful content, divided up as...
>2 pages of maps, one regional and one of the city the majority of the adventure takes place in.
>6 pages on the city of Korvosa, with overviews of the districts and important locations, as well as the various groups of people and notable citizens.
>4 pages on making adventurers that fit the city, from what the races are like to what different classes might be doing. Thanks to clerics, you get an overview of deities. Thanks to races, you get a look at the population statistics.
>2 pages of equipment, which allows you to distinguish the region slightly by the inclusion of the weapons of local ethnicities -- maybe you have a lot of pirates so you get some new pirate weapons and gear, or maybe you have a bunch of barbarians that fight with strange weapons and magic pastes to inspire rages.
>3 pages of Traits which also double as giving players ways to involve their character in the upcoming campaign while also giving them a minor mechanical benefit to draw help bait in interest.

Within those 17 pages, you've managed to get across a nice pitch of what the setting is like and various individuals they might meet or have met in the past. You've also sprinkled it with... 5 different feats -- or their equivalent in your game, since hopefully you aren't playing Pathfinder.

Compare that to their 69 page Guide to Korvosa, and guess how many players actually read through the entire thing. I generally find this approach to be the best, as it has a couple of nice little benefits.

One, I've already got this information for the setting in my head or notes, and placing it up on a wiki can help me organize and check myself. Maybe something doesn't make sense, maybe I have a weird gap in organizations, whatever. Actually processing through it and organizing it can help reveal things you might have overlooked. Secondly, cutting through a large chunk of content to get it down to a nice 15-20 pages of easily digestible content helps you focus yourself as you're basically coming up with a pitch for the setting or adventure, and that forces you to consider what's really important. Third, giving them a smaller pitch and a larger repository online allows the players that inevitably aren't super invested to still get tricked into getting slight familiarity with your setting in order to get to the crunch hidden inside like a tasty nougat while also allowing those that are more interested to be able to read at their leisure.

That's great advice, thanks.

One method that you see in a lot of old school materials is similar to some of the approaches in - turn it into mechanics.

Rather than a list of "here are the things that live in the Forbidden Woods", putting things in a random encounter table (optionally with percentages) says a lot about a region. If the Forbidden Woods has an encounter table full of undead and plantmen, this says something very different than an encounter table of goblins and spiders. You can alternately have players pick this up in play - either by direct experience or through rumours gleaned in taverns.

Happy to help. And while it might sound harsh, is pretty fucking spot-on about players. Most of them really don't care as much about your world as you do. That's pretty natural. Out of the... 9 or so people that I've run in my setting, two have actually read the wiki. But all of them read the hand-out, because inside was tasty nuggets that were relevant to character creation.

Take this doc I found a long time ago. It's a pretty nice template, and the world sounds quite interesting. But there's some things that I'd tweak. For one, by putting all of the crunch in an appendix at the end, he's basically given those rascally players an easy way out. Some might still flip through, but plenty will just give it the lightest skim and get their stats and move on. Also, a little too much art and a lot of it was stored at the very end instead of being sprinkled in. Shit doesn't even have to be commissioned, just something to help break up the pages of text and keep their interest.

The level of depth here would probably be best served by getting put on a wiki, and then the fat trimmed and turned into something injected with a little more crunch to be handed out for players making characters. System agnostic works for the Wiki, it will hurt you in the handout.

Derp, forgot the pdf.

I'll try something similar. Cool PDF and world there too.