They turned on their Human masters...

>they turned on their Human masters, believing themselves superior to the Humans who relied on the Men of Iron to do virtually everything for them. What followed next was an apocalyptic conflict known as the Cybernetic Revolt, a war so destructive it made the Horus Heresy seem small in scale. The Men of Iron employed world-consuming constructs, devices that could destroy suns, weapons that could throw entire continents into the heavens, and swarms of nano-machines that covered entire planets. However in the end, the Men of Iron were destroyed by an alliance of galactic powers.[3]

this sounds amazing
What did these men of iron look like? Where can I find a description?

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Here's my big question. When the Void Dragon awakens, will the Men of Iron return?

...

Men of Iron must be pretty shit to lose to a bunch of faggot pansies and xenos filth

It makes humanity of the past look so powerful. Why Eldars and Orks weren't finished back then? Why there are still Necron tombs inside of Imperium? If Men of Iron were so great and weren't the only piece of mankind's weaponry - why did humans never dominate he whole Milky Way, only the largest part of it?

Honestly I wish the Men of Iron had won. We wouldn't have to deal with all this Chaos, Ork, Necron, and Tyrannid shit if they had.

I just imagined how cool it would be if Borderlands were far more darker setting, rather than "top kek le memes" faggotry.

Orks can come back from literally nothing in a few years.

Eldar were even more powerful; there was a High Human culture, but no empire to go with it, which was something the Eldar possessed.

Why would they?

A little event called Old Night. Humanity was very well on its' way to conquering the whole galaxy, but then their entire means of FTL transport got stopped for 10k years, and then 10k years later one of the assholes leading the reunification decided to throw a hissy fit.

Past humanity wasn't the Imperium's humanity, they didn't wanted to destroy anything that wasn't them.