Hey Veeky Forums

im well aware of that

Nah, it still makes sense for natties. Real squats have many things that can cause you, depending on %1rm used, to fail at x reps. It's not only quad/ham fatigue; literally any small muscle could give out throwing off your balance, it can be CNS, it can be coordination. While with leg press, you can do many more reps, because it is a machine and that means zero balance and coordination requirements.
Squats >>> leg press, except in regards to quad and ham hypertrophy.

Literally any kind of squats as long as you take them (relatively) deep, deads/SLDLs. If those don't give you big meaty manthighs, you're a genetic dead end for sure.

Impossible, don't even try