How do i make a metroid Game work?

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Lots of planing.

Which Metroid game is that?

Anyone can do an atmospheric dungeon exploration game. Metroid specifically would be a fucking horrible idea to run as a roleplaying game, but something like a squad of players exploring a dark abandoned network of spaces could be done in nearly any system. The key element to it is actually in how well the DM handles *description*.

If you want them to sequence break the dungeons, play D&D.

look up Blood of the Chozo if you need some ideas.

I love the metroid games, but I really don't see them as a good basis for group-based adventuring. That said, It does have some elements you could incorporate in a sci-fi dungeon crawl:
1. Heavy emphasis on different environments, and how they affect and hinder the PCs. Examples include stifling (or lethal) heat, underwater sections, acid pools or even atmosphere, aggressively fast-growing vegetation, the list goes on.
2. Related, new and weird enemies for each environment that the players need to learn their way around; weaknesses, behavior, etc
3. Cool tech looted from the dungeon being the main source of PC empowerment.
4. Spectacular bossfights. Using a system that encourages tactics other than hitting them until they run out of hp helps.
5. Environmental storytelling. Have PCs figure stuff out more from clues they find rather than NPC talk.
Okay, wait, this was quite a substantial list. I COULD se this make a good game.

Try blowing on the cartridge.

Nice.

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Came here to say this.
+internet to you