Has philosophy come up with any relevant questions or answer regarding science in 21th century?

Has philosophy come up with any relevant questions or answer regarding science in 21th century?

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Yes

Care to elaborate a little bit?

No, it's like Latin. An outdated circlejerk.

No

Yes. Things such as dark matter, dark energy, strings, and basically any posited theories to explain observable phenomena that lack directly observable causes is a metaphysical claim rather than a scientific claim. Even questions such as the nature of matter and energy themselves (whether they are further reducible or fundamental; and if fundamental, then why?) are questions in metaphysics that science finds itself exploring. Also, the hard problem of consciousness--we're still unsure (even with all our knowledge about neuroscience, including knowledge of structures and functions in the brain) about the nature of subjective first-person experience. There is no consensus in the field and even the best neurosciences will admit that it's an extremely difficult problem, which is why it continues to be argued in philosophy today. (Though it's distinctly an interdisciplinary issue that involves neuroscience AND philosophy--we need to take into account third person facts as well as first person facts).
And then there's the matter of how can we really KNOW what is proven scientifically? Are our observations about the universe just in line with the consistency of the narrative, but not reflecting of profound truths? And so we have epistemology...
Basically philosophy exists for the purpose of seeking truth. Science evolved FROM philosophy.

cringe

cringe^2

The parts of (past) philosophy that aren't BS have their own names now.
So it's literally impossible today for philosophy to be useful, because it stops being called being philosophy the moment it does