>On 28 February 1998, Andrew Wakefield, a British gastroenterologist, and colleagues [1] published a paper in The Lancet that described 8 children whose first symptoms of autism appeared within 1 month after receiving an MMR vaccine. All 8 of these children had gastrointestinal symptoms and signs and lymphoid nodular hyperplasia revealed on endoscopy. From these observations, Wakefield postulated that MMR vaccine caused intestinal inflammation that led to translocation of usually nonpermeable peptides to the bloodstream and, subsequently, to the brain, where they affected development.
Do Vaccines Cause Autism?
Thomas Peterson
Lucas Sanders
>MMR -> intestinal inflammation
so did they find out whether there's a causal link there?
Josiah Gonzalez
Talk about jumping to conclusions.
Observations:
Children received vaccines
Children showed symptoms of autism within a month
Children displayed gastrointestinal symptoms and lymphoid nodular hyperplasia
Conclusions:
MMR vaccine caused intestinal inflammation. What evidence is there that the vaccine caused the inflammation as opposed to other environmental causes? Were the vaccinated children compared to non-vaccinated children?
Inflammation caused translocation of nonpermeable peptides into the bloodstream. Is there any evidence given for this, or does he jump straight from inflammation to the peptides? Were these peptides quantified or detected in any way?
The peptides affected development. What evidence is there to support this conclusion?
Really seems like he's jumping from A to Z. And going off his hypothesis, the vaccine didn't cause autism, the intestinal inflammation did, so anything that causes intestinal inflammation would cause autism.
And a quick google search shows that several people have tried to replicate these results and have been unsuccessful. Also that the children in the study were recruited by a lawyer preparing a lawsuit against the manufacturers of the MMR vaccine, and they paid Wakefield 400k for the research, which he didn't disclose. And that Wakefield subjected the children involved to colonoscopies and lumbar punctures not approved by the ethics board of the hospital he was at. Now The Lancet has retracted the paper an Wakefield has lost his medical license.
Gavin Williams
so 8 children had gastrointestinal symptoms and signs of lymphoid nodular hyperplasia, but the MMR is what caused the autism? There are no controls. How about children without GI symptoms that receive the MMR vaccine? How about children with GI symptoms that never received the MMR vaccine? Should MDs be allowed to do research?
Is this shit really the reason people think vaccines cause autism?
Zachary Harris
Does it matter?
Present company excluded, is autism worse than a measles outbreak?
Brayden Bell
yeah actually it is, I'd rather get measles once than have autism for life.
Adrian Hall
spotted the neurotypicals
Austin Allen
How 'bout getting measles for life?
B-because it kills you.
Dylan Russell
only if you're a pussy
Nathaniel Sanchez
, he said on Veeky Forums, without a trace of irony.