Do Vaccines Cause Autism?

>On 28 February 1998, Andrew Wakefield, a British gastroenterologist, and colleagues [1] published a paper in The Lancet that described 8 children whose first symptoms of autism appeared within 1 month after receiving an MMR vaccine. All 8 of these children had gastrointestinal symptoms and signs and lymphoid nodular hyperplasia revealed on endoscopy. From these observations, Wakefield postulated that MMR vaccine caused intestinal inflammation that led to translocation of usually nonpermeable peptides to the bloodstream and, subsequently, to the brain, where they affected development.

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en.m.wikipedia.org/wiki/Leaky_gut_syndrome
cbsnews.com/news/family-to-receive-15m-plus-in-first-ever-vaccine-autism-court-award/
twitter.com/NSFWRedditImage

>MMR -> intestinal inflammation
so did they find out whether there's a causal link there?

Talk about jumping to conclusions.

Observations:
Children received vaccines
Children showed symptoms of autism within a month
Children displayed gastrointestinal symptoms and lymphoid nodular hyperplasia

Conclusions:
MMR vaccine caused intestinal inflammation. What evidence is there that the vaccine caused the inflammation as opposed to other environmental causes? Were the vaccinated children compared to non-vaccinated children?

Inflammation caused translocation of nonpermeable peptides into the bloodstream. Is there any evidence given for this, or does he jump straight from inflammation to the peptides? Were these peptides quantified or detected in any way?

The peptides affected development. What evidence is there to support this conclusion?

Really seems like he's jumping from A to Z. And going off his hypothesis, the vaccine didn't cause autism, the intestinal inflammation did, so anything that causes intestinal inflammation would cause autism.

And a quick google search shows that several people have tried to replicate these results and have been unsuccessful. Also that the children in the study were recruited by a lawyer preparing a lawsuit against the manufacturers of the MMR vaccine, and they paid Wakefield 400k for the research, which he didn't disclose. And that Wakefield subjected the children involved to colonoscopies and lumbar punctures not approved by the ethics board of the hospital he was at. Now The Lancet has retracted the paper an Wakefield has lost his medical license.

so 8 children had gastrointestinal symptoms and signs of lymphoid nodular hyperplasia, but the MMR is what caused the autism? There are no controls. How about children without GI symptoms that receive the MMR vaccine? How about children with GI symptoms that never received the MMR vaccine? Should MDs be allowed to do research?

Is this shit really the reason people think vaccines cause autism?

Does it matter?

Present company excluded, is autism worse than a measles outbreak?

yeah actually it is, I'd rather get measles once than have autism for life.

spotted the neurotypicals

How 'bout getting measles for life?

B-because it kills you.

only if you're a pussy

, he said on Veeky Forums, without a trace of irony.

>Should MDs be allowed to do research?

Oh my god this, so many of these 'small clinical reports' are fucking nonsense. Not because of the data they produce, but because of the weight the authors (mostly MD's) put on their conclusions based on observations of correlation within tiny data sets with no controls and little to no actual statistical analysis.

>citing andrew wakefield

You know this guy was proven to be a fraud right?

Why do we allow MD's to do research. They aren't fucking scientists and usually only have a shallow understanding of most scientific disciplines.

Andrew Wakefield's hypothesis was dismissed without being thoroughly investigated. They worked backwards from the conclusion they wanted to find, decided to play the man not the ball, and effectively destroyed his career.

However, I think we now have enough evidence to safely conclude his hypothesis was wrong.

Autism is linked to intestinal inflammation, but not in the way Wakefield thought. Autism is triggered by propanoic acid, which is produced by the kind of gut bacteria which cause intestinal inflammation (and also tend to be the most resistant to antibiotics).

But the problems with gut bacteria are NOT the result of vaccination.

> While exposure to mercury may result in damage to brain, kidneys, and developing fetus,[3] the current scientific consensus has found no convincing scientific evidence supporting claims that -edit- mercury-based compounds -/edit- have such effects?

This is the problem with anti-vaccine fags. They don't know what the hell they're talking about.

> Thiomersal is an organomercury compound used as a preservative in vaccines since the 1930's

> rates of autism have continued to increase despite removal of thiomersal from vaccines.

Inter-generational autism

The real questions here from a medical perspective are others though
1) Do vaccines cause autism significantly more than any other thing?
2) Is the cost of autism greater than that of not-vaccinating to prevent it?

Since the answer to both of those questions is no and absolutely not, then the conclusion is people must keep getting vaccinated.

How many of generations of rat can you vaccinate with mercury before some defect sets in is the real question

Andrew Wakefields research was replicated numerous times with different results. The paper was both theoretically and empirically debunked, not to mention ethically bankrupt.

>muh leaky gut pseudoscience
Please go back to your mommy blog

Agreed

Try reading the whole post before replying to it.

I agree Andrew Wakefield's hypothesis was wrong.

...But it took years to RELIABLY reach that conclusion because instead of unbiased investigation with a bias skewed to discrediting him. Had they done a proper unbiased investigation, the link with propanoic acid would probably have been uncovered much earlier.

As for the ethics, I think the apparently (at the time) strong link justified thorough investigation.

Furthermore, the leaky gut phenomenon that was the basis of Wakefield's hypothesis is not pseudoscience. It is something that has been observed, and AIUI it is a common result of excessive alcohol consumption.

But AFAIK it is neither linked to vaccines nor autism.

>MMR vaccine prevents illness that cause sterility.
>Idiots won't get vaccinated.

I don't see what the problem is.

YES in fact they do. Though not the sole cause of autism.
With startling new evidence proving that vaccinations cause autism through disruption of the autoimmune system, causing the body to attack itself (much like cancer) Frequent infections as a child also cause autism. The effects of vaccines on the immune system are stochastic and can rarely lead to the tism.

Of course there was a bias towards discrediting him since the paper made no sense on its face.

>Furthermore, the leaky gut phenomenon that was the basis of Wakefield's hypothesis is not pseudoscience. It is something that has been observed, and AIUI it is a common result of excessive alcohol consumption.
Which quack blog did you read that?

en.m.wikipedia.org/wiki/Leaky_gut_syndrome
>Leaky gut syndrome
>pseudomedical diagnosis
>Leaky gut syndrome is a hypothetical, medically unrecognized condition.

Here's my favorite one. US gov awarded $1.5 million to a family
cbsnews.com/news/family-to-receive-15m-plus-in-first-ever-vaccine-autism-court-award/

>Wakefield

D R O P P E D

You should have kept on reading...

Autism is my Super Power.

Autistic is the master Race of Future. The New Übermensch.

I don't want a Cure.

Autistics excels at Science & Math

Autistics are Genius.

Newton & Einstein were Autistic. Bill Gates is Autistic.

Normies are Brainlet Scum Undermensch & must be enslaved.

No ???