Scientifically looking, what's the most effective combination of meds to kill yourself?

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There is some creepy correlation between being intelligent and being mentally unstable. Op is not the first one. It's sad if she's able to do such things which makes her hyper intelligent. It's sad nobody helped her. Don't feed her. We need people like her.
I remember her posts. There's something more than just spam and attention whoring. I guess she can't choose which side to take.

the truth is suicide is always the worst answer because you can just get so high you are living in a stupor.

especially if you are a girl....
That is what i did.

Always wanted to die, started thinking about it from a really young age, and i would set checkpoints like if i didnt do x by 18 i would off myself and while i never achieved anything (including what i wanted) despite having wealthy parents scrambling to save me from myself, i never killed myself.

Anyway i sort of "attempted" once with phenobarbital but didn't take enough, thats why i agreed with the other user about barbs, they are extraordinarily potent for the purpose of turning yourself off. I ended up staying with a friend for two days while the effects wore off. I was still seeing double at the end of the third day, it was nuts.

ANYWAY
The reason i responded to your post is because later on i compromised with myself that chemical suicide is the best of both worlds, you get to exist, but also not care about anything.
Heroin is perfect for that, and that's what i did, and here's how i got it.

Craigslist jobs, find something at a factory, interview.
If it's not a "scummy" place then dont take the job. Scummy plants usually only pay the majority of workers min or just above, the employees might have tattoos or dress gangster, and you wont really see much supervision. I've worked at two places like this and it's incredibly easy to find hard drugs here, and once you find hard drugs once it's really easy to keep finding them. I have social phobia and getting heroin this way was so easy, so i imagine anyone could do it.

Later on i kicked the heroin, and even later after that i realized how pointless feeling sorry for yourself is, which is something i had never realized.

It can but it wont if you're a healthy young person. Tried it years ago, woke up after 16 hours disoriented and my balance was off for the next week or so. Was confused most of the time after that incident.
en.wikipedia.org/wiki/Charcoal-burning_suicide
this seems to be more effective method but don't do it OP, seek help

Only do it if you want to troll the paramedics who will have to work overtime because of you being an attention whore

what alcohol? absinthe, vodka, rum, tequila, scotch...?

Just hire a prostitute to fuck you until you die of a heart attack.

If he was serious you're too late and I doubt sex would trigger a heart attack.

that's how my grandfather died.

All the people in this thread who unironically think that opioid/sedative overdoses are peaceful are retarded. IV, maybe (and even in lethal injection scenarios this frequently goes horribly wrong because of the huge variability in individual baseline sensitivity) - the sudden onset will cause unconsciousness, but with pills it is a slow rasping descent into respiratory failure. I have seen someone overdose from a light heroin injection and alcohol combination, and it wasn't pretty. I have a high natural tolerance and have taken two or three times the amount that individual has while on benzos and just fallen asleep reading a book with no respiratory distress. There is really no way to tell unless you're already familiar with your response to the combinations or you really go for an insane sledgehammer dose or synergistic triple combo.

By the way, the interesting corollary of the low risk of overdosing on heroin alone is the fact that as many as 50% of accidental overdoses may actually be suicides. This was in a metareview I read ages ago. IV recreational heroin use has a therapeutic index of about 7.5 (lower than you'd expect when fentanyl has a TI of 270 and morphine 50~ because non-therapeutic use raises the minimum effect dose), and modern heroin is usually more than 20% pure. You'd need to get a bag of pharmaceutical grade skag to die of a purity OD unless your gear is really stepped on.

There is a way to die painlessly and rapidly in a common household item but this must remain a secret of the pharmaceutical chemists' guild.